Ictal cerebral haemodynamics of childhood epilepsy measured with near-infrared spectrophotometry

Ictal cerebral haemodynamics of childhood epilepsy measured with near-infrared spectrophotometry.

Near-infrared spectrophotometry (NIRS) is a new technique that allows continuous non-invasive monitoring of tissue oxygenation and haemodynamics in the brain. We used NIRS in various types of paediatric epileptic seizures in order to understand the pathophysiology of epileptic seizures in childhood epilepsy. This study examined 15 children ranging in age from 1.5 months to 16 years (nine males ...

Cerebral autoregulation in the microvasculature measured with near-infrared spectroscopy.

Cerebral autoregulation (CA) is the mechanism that allows the brain to maintain a stable blood flow despite changes in blood pressure. Dynamic CA can be quantified based on continuous measurements of systemic mean arterial pressure (MAP) and global cerebral blood flow. Here, we show that dynamic CA can be quantified also from local measurements that are sensitive to the microvasculature. We use...

Ictal Functional Neuroimaging of Childhood Absence Epilepsy

ICTAL FUNCTIONAL NEUROIMAGING OF CHILDHOOD ABSENCE EPILEPSY Matthew Vestal (Sponsored by Hal Blumenfeld). Departments of Neurology, Neurobiology, and Neurosurgery, Yale University School of Medicine, New Haven, CT. Absence seizures in Childhood Absence Epilepsy (CAE) are 5 – 10 second episodes of impaired consciousness that are characterized on electroencephalography (EEG) by frontally-predomin...

Effect of nuchal cord on fetal cerebral haemodynamics and oxygenation measured by near infrared spectroscopy during labour.

OBJECTIVE To test the hypothesis that a nuchal cord has a significant effect upon fetal cerebral haemodynamics and oxygenation during labour. STUDY DESIGN A specially designed optical probe was inserted through the dilated cervix and placed against the scalp of 37 fetuses during labour in a teaching hospital obstetric unit. Changes in total cerebral haemoglobin concentration were measured con...

Portable Refrigerant Identification by Near Infrared Spectrophotometry